The 2021 Emergency Nurse Practitioner (ENP) Competencies represents the integration of previously published competencies from both the American Academy of Emergency Nurse Practitioners (AAENP, 2018) and the Emergency Nurses Association (ENA, 2019). This document used an external validation process for review and revision of these competencies which are aligned with other national initiatives and documents that shape and define Nurse Practitioner curricular development. The resulting unified set of ENP competencies support current regulatory frameworks, credentialing and insurer challenges.