Prevention of Blood Specimen Hemolysis in Peripherally-Collected Venous Specimens CPG Synopsis-Prevention of Blood Specimen Hemolysis in Peripherally-Collected Venous Specimens CPG Synopsis

Prevention of Blood Specimen Hemolysis in Peripherally-Collected Venous Specimens CPG Synopsis

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The Clinical Practice Guideline focuses on the prevention of hemolysis in blood specimens collected from peripheral veins. Hemolysis can lead to inaccurate results, requiring repeat collection and causing delays in treatment decisions. The guideline reviews the scientific evidence for preventing hemolysis in the preanalytic phase. <br /><br />Some of the recommendations for preventing hemolysis before the blood draw include educating staff on phlebotomy techniques, using straight needles instead of intravenous catheters, and using low vacuum and low volume tubes. The evidence regarding the influence of personnel and needle or catheter gauges on hemolysis is conflicting. Similarly, there is conflicting evidence regarding the use of syringes versus vacuum tubes for blood collection.<br /><br />During and after the blood draw, it is suggested to draw blood from the antecubital fossa, minimize tourniquet application time, and fill vacuum tubes to their recommended volume. The evidence regarding the use of needleless connectors or extension tubing and the use of pneumatic tube systems is conflicting. There is insufficient evidence to determine the association between perceived difficulty of intravenous catheter insertion and the risk of hemolysis. Monitoring hemolysis rates and providing feedback to the staff performing phlebotomy also lacks sufficient evidence.<br /><br />The guideline provides levels of recommendation based on the quality and consistency of evidence. Level A (High) recommendations have consistent and good quality evidence, while Level B (Moderate) recommendations have minor inconsistencies in quality evidence. Level C (Weak) recommendations have limited or low-quality evidence, and NR (Not Recommended) indicates that the practice is not recommended based on current evidence. IE (Insufficient Evidence) means there is not enough evidence to make a recommendation, and NE (No Evidence) indicates a lack of evidence.<br /><br />Overall, the guideline presents evidence-based recommendations to prevent hemolysis during the collection and transportation of peripheral venous blood specimens.

Meta Tag

hemolysis CPG

hemolysis blood

hemolysis culture

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hemolysis infection

hemolysis sepsis

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Keywords

hemolysis prevention

blood specimens

phlebotomy techniques

low vacuum

low volume tubes

syringes

vacuum tubes

antecubital fossa

tourniquet application

evidence-based recommendations