Intranasal Medication Administration CPG Synopsis-Intranasal Medication Administration CPG Synopsis

Intranasal Medication Administration CPG Synopsis

Pdf Summary

This Clinical Practice Guideline (CPG) evaluates the effectiveness of intranasal medication administration for emergency care patients. Multiple studies have shown that intranasal fentanyl can safely and effectively treat moderate to severe pain in adults and children aged 1-18 years. IN glucagon has also been found to be non-inferior to intramuscular glucagon for treating acute hypoglycemia in both adults and children and adolescents aged 4-17 years. IN ketamine is safe and effective for managing pain in adults and children aged 3-18 years. IN ketorolac can be used for short-term acute pain treatment in adults. IN naloxone is a safe and effective agent for reversing the acute effects of opioids. IN sufentanil can be used to treat moderate to severe pain in adults. IN diazepam may be effective for treating acute seizures in adult patients. IN isopropyl alcohol can reduce nausea in adults. IN midazolam can manage acute seizures and be used as a sedative and anxiolytic in children. IN lorazepam may be effective for seizure control in children. IN morphine provides pain reduction in adult patients. IN dexmedetomidine is not recommended for use as an adjunctive sedative for pediatric patients in the ED due to insufficient evidence. There is also insufficient evidence to support the use of IN fentanyl and nitrous oxide combination, IN hydromorphone, and midazolam, ketamine, and fentanyl combination in the emergency setting. There is no recommended commercially available device or method for IN medication administration, although expert opinion suggests that using a mucosal atomization device may be more effective than the dripping method. The levels of recommendation in this guideline vary from A (high) to N/R (not recommended) based on the quality and consistency of evidence.

Meta Tag

intranasal medication

intranasal meds

intranasal drug

intranasal CPG

intranasal fentanyl

intranasal morphine

intranasal diazepam

intranasal lorazepam

intranasal sufentanil

intranasal hydromorphone

intranasal glucagon

intranasal naloxone

intranasal ketamine

intranasal ketorolac

intranasal midazolam

intranasal analgesics

intranasal IN

intranasal sedation

intranasal paramedic

intranasal antiemetic

intranasal clinical practice guideline

Keywords

intranasal medication administration

emergency care patients

intranasal fentanyl

moderate to severe pain

IN glucagon

acute hypoglycemia

IN ketamine

pain management

IN naloxone

opioid reversal