GLP-1 Agonists: What Does an Emergency Department Nurse Need to Know-References

References

Pdf Summary

This collection of references centers on glucagon-like peptide-1 (GLP-1) receptor agonists, focusing on their clinical roles, emergent applications, and considerations particularly relevant for emergency department nurses and clinicians.<br /><br />GLP-1 agonists, originally developed for type 2 diabetes management, have expanded uses including weight loss, cardiovascular benefits, and potential treatment of other chronic conditions (Allen et al., 2024; Iorga et al., 2020; Prasad-Reddy & Isaacs, 2015; Richman, 2023). Their mechanisms extend beyond pancreatic effects, influencing gastric emptying and metabolic pathways (Zhao et al., 2021; Fujino et al., 2023).<br /><br />Emergency clinicians need awareness of both therapeutic benefits and risks. Studies highlight gastrointestinal adverse events such as intestinal obstruction and delayed gastric emptying associated with GLP-1 agonists (Gudin et al., 2020; Sodhi et al., 2023). These effects have important implications for patient assessment in emergency settings, particularly in interpreting symptoms and managing anesthesia (Fujino et al., 2023). Additionally, the untapped potential for GLP-1 agonists in hospitalized patients warrants clinical attention (Mustafa & Whyte, 2019).<br /><br />Practical concerns also arise regarding medication access and safety, including the rise of compounded formulations and online purchases, which may pose risks (Lupkin, 2024; American Pharmacists Association, 2024).<br /><br />Overall, this literature underscores the importance for emergency nurses to understand the evolving clinical landscape of GLP-1 agonists—recognizing their expanding therapeutic uses, side effect profiles, and implications for acute care treatment to ensure patient safety and optimize outcomes (Long & Perera, 2024; Brunton & Wysham, 2020).

Keywords

GLP-1 receptor agonists

type 2 diabetes management

weight loss

cardiovascular benefits

gastrointestinal adverse events

emergency department nursing

delayed gastric emptying

intestinal obstruction

medication safety

compounded formulations