Clinical Practice Guideline: Intranasal Medication Administration-Clinical Practice Guideline: Intranasal Medication Administration

Clinical Practice Guideline: Intranasal Medication Administration

Pdf Summary

Intranasal medication administration is an effective and safe route for delivering medications in the emergency care setting. It offers advantages such as easy accessibility, rapid onset of action, and high patient acceptability. Medications like fentanyl, hydromorphone, morphine, ketamine, diazepam, lorazepam, and midazolam have shown effectiveness when administered intranasally for pain relief, sedation, and seizure treatment. Combination medications and isopropyl alcohol inhalation have also been used successfully. Intranasal glucagon is comparable to injectable glucagon for treating hypoglycemia, while intranasal naloxone is a safe and effective alternative for opioid overdoses. Intranasal medication administration is well-tolerated and generally results in high patient satisfaction, especially in pediatric patients. More research is needed to further establish the safety and efficacy of this administration route in different patient populations and for other medications. The studies reviewed have minor flaws or inconsistencies, indicating the need for further research on optimal dosing, side effects, and long-term effects in the emergency care setting.

Keywords

Intranasal medication administration

emergency care

medications

fentanyl

hydromorphone

morphine

ketamine

diazepam

lorazepam

midazolam